Cargando…

Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers

Antennaria dioica (L.) Gaertn. and Helichrysum arenarium (L.) Moench. are two species of the Asteraceae family, known in Romanian traditional medicine for their diuretic, choleretic, and anti-inflammatory properties. The aim of the present study was to evaluate the phenolic and sterolic composition...

Descripción completa

Detalles Bibliográficos
Autores principales: Babotă, Mihai, Mocan, Andrei, Vlase, Laurian, Crișan, Ovidiu, Ielciu, Irina, Gheldiu, Ana-Maria, Vodnar, Dan Cristian, Crișan, Gianina, Păltinean, Ramona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017730/
https://www.ncbi.nlm.nih.gov/pubmed/29438342
http://dx.doi.org/10.3390/molecules23020409
_version_ 1783334812187099136
author Babotă, Mihai
Mocan, Andrei
Vlase, Laurian
Crișan, Ovidiu
Ielciu, Irina
Gheldiu, Ana-Maria
Vodnar, Dan Cristian
Crișan, Gianina
Păltinean, Ramona
author_facet Babotă, Mihai
Mocan, Andrei
Vlase, Laurian
Crișan, Ovidiu
Ielciu, Irina
Gheldiu, Ana-Maria
Vodnar, Dan Cristian
Crișan, Gianina
Păltinean, Ramona
author_sort Babotă, Mihai
collection PubMed
description Antennaria dioica (L.) Gaertn. and Helichrysum arenarium (L.) Moench. are two species of the Asteraceae family, known in Romanian traditional medicine for their diuretic, choleretic, and anti-inflammatory properties. The aim of the present study was to evaluate the phenolic and sterolic composition of flowers from the two species and to assess their antioxidant, antibacterial and antifungal properties. LC-MS analyses were performed on methanolic, ethanolic and 70% v/v ethanolic extracts, before and after acid hydrolysis, and revealed high amounts of polyphenols. Chlorogenic acid was found as the main compound for the flowers of A. dioica (502.70 ± 25.11 mg/100 g d.w.), while quercitrin was dominant in H. arenarium (424.28 ± 21.21 mg/100 g d.w.) in 70% v/v ethanolic extracts before hydrolysis. Antioxidant capacity assays showed an important antioxidant potential, which can be correlated with the determined polyphenolic compounds, showing the 70% v/v ethanolic extracts of the two species as being the most effective antioxidant samples for the DPPH assay. Antibacterial and antifungal assays confirm a modest biological potential for the same extract of both species. Results obtained in the present study bring important data and offer scientific evidence on the chemical composition and on the biological activities of the flowers belonging to the two species.
format Online
Article
Text
id pubmed-6017730
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-60177302018-11-13 Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers Babotă, Mihai Mocan, Andrei Vlase, Laurian Crișan, Ovidiu Ielciu, Irina Gheldiu, Ana-Maria Vodnar, Dan Cristian Crișan, Gianina Păltinean, Ramona Molecules Article Antennaria dioica (L.) Gaertn. and Helichrysum arenarium (L.) Moench. are two species of the Asteraceae family, known in Romanian traditional medicine for their diuretic, choleretic, and anti-inflammatory properties. The aim of the present study was to evaluate the phenolic and sterolic composition of flowers from the two species and to assess their antioxidant, antibacterial and antifungal properties. LC-MS analyses were performed on methanolic, ethanolic and 70% v/v ethanolic extracts, before and after acid hydrolysis, and revealed high amounts of polyphenols. Chlorogenic acid was found as the main compound for the flowers of A. dioica (502.70 ± 25.11 mg/100 g d.w.), while quercitrin was dominant in H. arenarium (424.28 ± 21.21 mg/100 g d.w.) in 70% v/v ethanolic extracts before hydrolysis. Antioxidant capacity assays showed an important antioxidant potential, which can be correlated with the determined polyphenolic compounds, showing the 70% v/v ethanolic extracts of the two species as being the most effective antioxidant samples for the DPPH assay. Antibacterial and antifungal assays confirm a modest biological potential for the same extract of both species. Results obtained in the present study bring important data and offer scientific evidence on the chemical composition and on the biological activities of the flowers belonging to the two species. MDPI 2018-02-13 /pmc/articles/PMC6017730/ /pubmed/29438342 http://dx.doi.org/10.3390/molecules23020409 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Babotă, Mihai
Mocan, Andrei
Vlase, Laurian
Crișan, Ovidiu
Ielciu, Irina
Gheldiu, Ana-Maria
Vodnar, Dan Cristian
Crișan, Gianina
Păltinean, Ramona
Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers
title Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers
title_full Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers
title_fullStr Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers
title_full_unstemmed Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers
title_short Phytochemical Analysis, Antioxidant and Antimicrobial Activities of Helichrysum arenarium (L.) Moench. and Antennaria dioica (L.) Gaertn. Flowers
title_sort phytochemical analysis, antioxidant and antimicrobial activities of helichrysum arenarium (l.) moench. and antennaria dioica (l.) gaertn. flowers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017730/
https://www.ncbi.nlm.nih.gov/pubmed/29438342
http://dx.doi.org/10.3390/molecules23020409
work_keys_str_mv AT babotamihai phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT mocanandrei phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT vlaselaurian phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT crisanovidiu phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT ielciuirina phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT gheldiuanamaria phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT vodnardancristian phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT crisangianina phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers
AT paltineanramona phytochemicalanalysisantioxidantandantimicrobialactivitiesofhelichrysumarenariumlmoenchandantennariadioicalgaertnflowers