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Functional Impact of the N-terminal Arm of Proline Dehydrogenase from Thermus thermophilus

Proline dehydrogenase (ProDH) is a ubiquitous flavoenzyme that catalyzes the oxidation of proline to Δ(1)-pyrroline-5-carboxylate. Thermus thermophilus ProDH (TtProDH) contains in addition to its flavin-binding domain an N-terminal arm, consisting of helices αA, αB, and αC. Here, we report the bioch...

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Detalles Bibliográficos
Autores principales: Huijbers, Mieke M. E., van Alen, Ilona, Wu, Jenny W., Barendregt, Arjan, Heck, Albert J. R., van Berkel, Willem J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017737/
https://www.ncbi.nlm.nih.gov/pubmed/29337919
http://dx.doi.org/10.3390/molecules23010184