Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex

The host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8]) was studied by (1)H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in t...

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Autores principales: Xia, Yu, Wang, Chuan-Zeng, Tian, Mengkui, Tao, Zhu, Ni, Xin-Long, Prior, Timothy J., Redshaw, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017755/
https://www.ncbi.nlm.nih.gov/pubmed/29342978
http://dx.doi.org/10.3390/molecules23010175
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author Xia, Yu
Wang, Chuan-Zeng
Tian, Mengkui
Tao, Zhu
Ni, Xin-Long
Prior, Timothy J.
Redshaw, Carl
author_facet Xia, Yu
Wang, Chuan-Zeng
Tian, Mengkui
Tao, Zhu
Ni, Xin-Long
Prior, Timothy J.
Redshaw, Carl
author_sort Xia, Yu
collection PubMed
description The host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8]) was studied by (1)H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in the hydrophobic cavity of the Q[8] host to form a ternary complex for the first time.
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spelling pubmed-60177552018-11-13 Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex Xia, Yu Wang, Chuan-Zeng Tian, Mengkui Tao, Zhu Ni, Xin-Long Prior, Timothy J. Redshaw, Carl Molecules Communication The host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8]) was studied by (1)H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in the hydrophobic cavity of the Q[8] host to form a ternary complex for the first time. MDPI 2018-01-15 /pmc/articles/PMC6017755/ /pubmed/29342978 http://dx.doi.org/10.3390/molecules23010175 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Xia, Yu
Wang, Chuan-Zeng
Tian, Mengkui
Tao, Zhu
Ni, Xin-Long
Prior, Timothy J.
Redshaw, Carl
Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex
title Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex
title_full Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex
title_fullStr Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex
title_full_unstemmed Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex
title_short Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex
title_sort host-guest interaction of cucurbit[8]uril with n-(3-aminopropyl)cyclohexylamine: cyclohexyl encapsulation triggered ternary complex
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017755/
https://www.ncbi.nlm.nih.gov/pubmed/29342978
http://dx.doi.org/10.3390/molecules23010175
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