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4-Thiazolidinone Derivatives as MMP Inhibitors in Tissue Damage: Synthesis, Biological Evaluation and Docking Studies

Nine 2-(1,2-benzothiazol-3-yl)-N-(4-oxo-2-phenyl-1,3-thiazolidin-3-yl)propanamides combining a benzisothiazole and 4-thiazolidinone in one framework were designed and synthesized. The aim of the study was to verify their effectiveness to affect the inflammatory/oxidative process in which free oxygen...

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Detalles Bibliográficos
Autores principales: Incerti, Matteo, Crascì, Lucia, Vicini, Paola, Aki, Esin, Yalcin, Ismail, Ertan-Bolelli, Tugba, Cardile, Venera, Graziano, Adriana Carol Eleonora, Panico, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017844/
https://www.ncbi.nlm.nih.gov/pubmed/29443898
http://dx.doi.org/10.3390/molecules23020415

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