Cargando…

Recent Advances in Detecting Mitochondrial DNA Heteroplasmic Variations

The co-existence of wild-type and mutated mitochondrial DNA (mtDNA) molecules termed heteroplasmy becomes a research hot point of mitochondria. In this review, we listed several methods of mtDNA heteroplasmy research, including the enrichment of mtDNA and the way of calling heteroplasmic variations....

Descripción completa

Detalles Bibliográficos
Autores principales:	Duan, Mengqin, Tu, Jing, Lu, Zuhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017848/ https://www.ncbi.nlm.nih.gov/pubmed/29401641 http://dx.doi.org/10.3390/molecules23020323

Ejemplares similares

Detection of Heteroplasmic Mitochondrial DNA in Single Mitochondria
por: Reiner, Joseph E., et al.
Publicado: (2010)

Heteroplasmic mitochondrial DNA variants in cardiovascular diseases
por: Calabrese, Claudia, et al.
Publicado: (2022)

Heteroplasmic mitochondrial DNA mutations in normal and tumor cells
por: He, Yiping, et al.
Publicado: (2010)

Heteroplasmic mitochondrial DNA mutations in frontotemporal lobar degeneration
por: Nie, Yu, et al.
Publicado: (2022)

Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila
por: Kandul, Nikolay P., et al.
Publicado: (2016)

Heteroplasmic Variants of Mitochondrial DNA in Atherosclerotic Lesions of Human Aortic Intima
por: Sobenin, Igor A., et al.
Publicado: (2019)

Recent Advances in Experimental Whole Genome Haplotyping Methods
por: Huang, Mengting, et al.
Publicado: (2017)

The Detection and Partial Localisation of Heteroplasmic Mutations in the Mitochondrial Genome of Patients with Diabetic Retinopathy
por: Malik, Afshan N., et al.
Publicado: (2019)

Detecting Rare Triple Heteroplasmic Substitutions in the Mitochondrial DNA Control Region: A Potential Concern for Forensic DNA Studies
por: Morovvati, Saeid, et al.
Publicado: (2011)

Heteroplasmic mitochondrial genomes of a Raillietina tapeworm in wild Pangolin
por: Tuli, Merga Daba, et al.
Publicado: (2022)

Halibut mitochondrial genomes contain extensive heteroplasmic tandem repeat arrays involved in DNA recombination
por: Mjelle, Kenneth A, et al.
Publicado: (2008)

Lack of Structural Variation but Extensive Length Polymorphisms and Heteroplasmic Length Variations in the Mitochondrial DNA Control Region of Highly Inbred Crested Ibis, Nipponia nippon
por: He, Xue-Lian, et al.
Publicado: (2013)

Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer
por: Li, Yanni, et al.
Publicado: (2023)

Pathogenic Heteroplasmic Somatic Mitochondrial DNA Mutation Confers Platinum-Resistance and Recurrence of High-Grade Serous Ovarian Cancer
por: Ni, Jing, et al.
Publicado: (2020)

Intraspecific and heteroplasmic variations, gene losses and inversions in the chloroplast genome of Astragalus membranaceus
por: Lei, Wanjun, et al.
Publicado: (2016)

Mitochondrial targeting of recombinant RNAs modulates the level of a heteroplasmic mutation in human mitochondrial DNA associated with Kearns Sayre Syndrome
por: Comte, Caroline, et al.
Publicado: (2013)

Oxygen tension modulates the mitochondrial genetic bottleneck and influences the segregation of a heteroplasmic mtDNA variant in vitro
por: Pezet, Mikael G., et al.
Publicado: (2021)

Data on heteroplasmic mutations in mitochondrial genomes of loggerhead and hawksbill sea turtles: First approach
por: Delgado-Cano, David, et al.
Publicado: (2019)

Deleterious heteroplasmic mitochondrial mutations are associated with an increased risk of overall and cancer-specific mortality
por: Hong, Yun Soo, et al.
Publicado: (2023)

Reducing the Number of Mismatches between Hairs and Buccal References When Analysing mtDNA Heteroplasmic Variation by Massively Parallel Sequencing
por: van der Gaag, Kristiaan J., et al.
Publicado: (2020)

A persistent mitochondrial deletion reduces fitness and sperm performance in heteroplasmic populations of C. elegans
por: Liau, Wei-Siang, et al.
Publicado: (2007)

Multiple Conserved Heteroplasmic Sites in tRNA Genes in the Mitochondrial Genomes of Terrestrial Isopods (Oniscidea)
por: Chandler, Christopher H., et al.
Publicado: (2015)

Direct genome-wide identification of G-quadruplex structures by whole-genome resequencing
por: Tu, Jing, et al.
Publicado: (2021)

Structure-Related Differences between Cytochrome Oxidase I Proteins in a Stable Heteroplasmic Mitochondrial System
por: Skibinski, David O F, et al.
Publicado: (2017)

An efficient strategy for a controllable droplet merging system for digital analysis
por: Qiao, Yi, et al.
Publicado: (2018)

Fabrication of a microfluidic chip based on the pure polypropylene material
por: Liang, Fupeng, et al.
Publicado: (2018)

Hotspot Selective Preference of the Chimeric Sequences Formed in Multiple Displacement Amplification
por: Tu, Jing, et al.
Publicado: (2017)

Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse
por: Filograna, R., et al.
Publicado: (2019)

Organelle bottlenecks facilitate evolvability by traversing heteroplasmic fitness valleys
por: Radzvilavicius, Arunas L., et al.
Publicado: (2022)

A Naturally Heteroplasmic Clam Provides Clues about the Effects of Genetic Bottleneck on Paternal mtDNA
por: Iannello, Mariangela, et al.
Publicado: (2021)

Plant organellar genomes utilize gene conversion to drive heteroplasmic sorting
por: Schaffner, Samantha H., et al.
Publicado: (2022)

Application of Solid-State Nanopore in Protein Detection
por: Luo, Yuhan, et al.
Publicado: (2020)

Elimination of Mutant mtDNA by an Optimized mpTALEN Restores Differentiation Capacities of Heteroplasmic MELAS-iPSCs
por: Yahata, Naoki, et al.
Publicado: (2020)

Recent advances in biological nanopores for nanopore sequencing, sensing and comparison of functional variations in MspA mutants
por: Bhatti, Huma, et al.
Publicado: (2021)

An Inherited Heteroplasmic Mutation in Mitochondrial Gene COI in a Patient with Prostate Cancer Alters Reactive Oxygen, Reactive Nitrogen and Proliferation
por: Arnold, Rebecca S., et al.
Publicado: (2013)

Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness
por: Meshnik, Lana, et al.
Publicado: (2022)

Editor’s Note: A Naturally Heteroplasmic Clam Provides Clues about the Effects of Genetic Bottleneck on Paternal mtDNA
Publicado: (2021)

The complete mitochondrial genome sequence of Boechera stricta
por: Li, Junji, et al.
Publicado: (2018)

Recent Advances in DNA Nanotechnology-Enabled Biosensors for Virus Detection
por: Yuwen, Lihui, et al.
Publicado: (2023)

Ketogenic treatment reduces the percentage of a LHON heteroplasmic mutation and increases mtDNA amount of a LHON homoplasmic mutation
por: Emperador, Sonia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7hul31ni3809ksojp9cpa2k7ud