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Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors

This work aims to synthesize new trehalase inhibitors selective towards the insect trehalase versus the porcine trehalase, in view of their application as potentially non-toxic insecticides and fungicides. The synthesis of a new pseudodisaccharide mimetic 8, by means of a stereoselective α-glucosyla...

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Detalles Bibliográficos
Autores principales: D’Adamio, Giampiero, Forcella, Matilde, Fusi, Paola, Parenti, Paolo, Matassini, Camilla, Ferhati, Xhenti, Vanni, Costanza, Cardona, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017881/
https://www.ncbi.nlm.nih.gov/pubmed/29462919
http://dx.doi.org/10.3390/molecules23020436