Cargando…
Novel Topologically Complex Scaffold Derived from Alkaloid Haemanthamine
The generation of natural product-like compound collections has become an important area of research due to low hit rates found with synthetic high-throughput libraries. One method of generating compounds occupying the areas of chemical space not accessible to synthetic planar heterocyclic structure...
Autores principales: | Govindaraju, Karthik, Masi, Marco, Colin, Margaux, Mathieu, Veronique, Evidente, Antonio, Hudnall, Todd W., Kornienko, Alexander |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017887/ https://www.ncbi.nlm.nih.gov/pubmed/29382096 http://dx.doi.org/10.3390/molecules23020255 |
Ejemplares similares
-
Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s Disease
por: Kohelová, Eliška, et al.
Publicado: (2019) -
In Vitro Effects of Fungal Phytotoxins on Cancer Cell Viability: First Insight into Structure Activity Relationship of a Potent Metabolite of Cochliobolus australiensis Radicinin
por: Mathieu, Veronique, et al.
Publicado: (2022) -
Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells
por: Mathieu, Veronique, et al.
Publicado: (2022) -
The Chemical Synthesis of the Crinine and Haemanthamine Alkaloids: Biologically Active and Enantiomerically-Related Systems that Serve as Vehicles for Showcasing New Methodologies for Molecular Assembly †
por: Hu, Nan, et al.
Publicado: (2021) -
Slight changes in the chemical structure of haemanthamine greatly influence the effect of the derivatives on rumen fermentation in vitro
por: Ramos-Morales, Eva, et al.
Publicado: (2019)