Cargando…
In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives
A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polyc...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017889/ https://www.ncbi.nlm.nih.gov/pubmed/29690598 http://dx.doi.org/10.3390/molecules23040979 |
_version_ | 1783334849325563904 |
---|---|
author | Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng |
author_facet | Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng |
author_sort | Zhang, Qiu-Chi |
collection | PubMed |
description | A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polycyclic structures in minimal steps remains a subject of great interest in both academia and industry. Herein we report an efficient method to assemble aryldihydronaphthalene derivatives via a cascade reaction of diarylalkynes with acrylates under the catalysis of a combined Lewis acid derived from In(III) salt and TMSBr. |
format | Online Article Text |
id | pubmed-6017889 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60178892018-11-13 In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng Molecules Communication A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polycyclic structures in minimal steps remains a subject of great interest in both academia and industry. Herein we report an efficient method to assemble aryldihydronaphthalene derivatives via a cascade reaction of diarylalkynes with acrylates under the catalysis of a combined Lewis acid derived from In(III) salt and TMSBr. MDPI 2018-04-23 /pmc/articles/PMC6017889/ /pubmed/29690598 http://dx.doi.org/10.3390/molecules23040979 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Zhang, Qiu-Chi Zhang, Wen-Wei Shen, Liang Shen, Zhi-Liang Loh, Teck-Peng In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
title | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
title_full | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
title_fullStr | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
title_full_unstemmed | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
title_short | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
title_sort | in(iii)-tmsbr-catalyzed cascade reaction of diarylalkynes with acrylates for the synthesis of aryldihydronaphthalene derivatives |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017889/ https://www.ncbi.nlm.nih.gov/pubmed/29690598 http://dx.doi.org/10.3390/molecules23040979 |
work_keys_str_mv | AT zhangqiuchi iniiitmsbrcatalyzedcascadereactionofdiarylalkyneswithacrylatesforthesynthesisofaryldihydronaphthalenederivatives AT zhangwenwei iniiitmsbrcatalyzedcascadereactionofdiarylalkyneswithacrylatesforthesynthesisofaryldihydronaphthalenederivatives AT shenliang iniiitmsbrcatalyzedcascadereactionofdiarylalkyneswithacrylatesforthesynthesisofaryldihydronaphthalenederivatives AT shenzhiliang iniiitmsbrcatalyzedcascadereactionofdiarylalkyneswithacrylatesforthesynthesisofaryldihydronaphthalenederivatives AT lohteckpeng iniiitmsbrcatalyzedcascadereactionofdiarylalkyneswithacrylatesforthesynthesisofaryldihydronaphthalenederivatives |