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Asymmetric Conjugate Addition of α,α-Disubstituted Aldehydes to Nitroalkenes Organocatalyzed by Chiral Monosalicylamides from trans-Cyclohexane-1,2-Diamines

Primary amine-salicylamides derived from chiral trans-cyclohexane-1,2-diamines are used as organocatalysts for the enantioselective conjugate addition of α,α-disubstituted aldehydes to arylated and heteroarylated nitroalkenes. The reaction is performed in the presence of 4-dimethylaminopyridine as a...

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Detalles Bibliográficos
Autores principales:	Martínez-Guillén, José R., Flores-Ferrándiz, Jesús, Gómez, Cecilia, Gómez-Bengoa, Enrique, Chinchilla, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017890/ https://www.ncbi.nlm.nih.gov/pubmed/29324713 http://dx.doi.org/10.3390/molecules23010141

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