Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies

Recently, thioxanthone derivatives were found to protect cells against toxic P-glycoprotein (P-gp) substrates, acting as potent inducers/activators of this efflux pump. The study of new P-gp chiral modulators produced from thioxanthone derivatives could clarify the enantioselectivity of this ABC tra...

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Detalles Bibliográficos
Autores principales: Lopes, Ana, Martins, Eva, Silva, Renata, Pinto, Madalena M. M., Remião, Fernando, Sousa, Emília, Fernandes, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017912/
https://www.ncbi.nlm.nih.gov/pubmed/29534440
http://dx.doi.org/10.3390/molecules23030626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017912/
https://www.ncbi.nlm.nih.gov/pubmed/29534440
http://dx.doi.org/10.3390/molecules23030626

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