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Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies
Recently, thioxanthone derivatives were found to protect cells against toxic P-glycoprotein (P-gp) substrates, acting as potent inducers/activators of this efflux pump. The study of new P-gp chiral modulators produced from thioxanthone derivatives could clarify the enantioselectivity of this ABC tra...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017912/ https://www.ncbi.nlm.nih.gov/pubmed/29534440 http://dx.doi.org/10.3390/molecules23030626 |