Cargando…

Sensitive Detection of 8-Nitroguanine in DNA by Chemical Derivatization Coupled with Online Solid-Phase Extraction LC-MS/MS

8-Nitroguanine (8-nitroG) is a major mutagenic nucleobase lesion generated by peroxynitrite during inflammation and has been used as a potential biomarker to evaluate inflammation-related carcinogenesis. Here, we present an online solid-phase extraction (SPE) LC-MS/MS method with 6-methoxy-2-naphthy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Chiung-Wen, Chang, Yuan-Jhe, Chen, Jian-Lian, Hsu, Yu-Wen, Chao, Mu-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017919/ https://www.ncbi.nlm.nih.gov/pubmed/29517997 http://dx.doi.org/10.3390/molecules23030605

Ejemplares similares

Quantification of Alfacalcidol Tablets Dissolution Content by Chemical Derivatization and LC-MS
por: Liu, Yang, et al.
Publicado: (2020)

Monitoring diacylglycerols in biofluids by non-isotopically paired charge derivatization combined with LC-MS/MS
por: Liu, Yang-Dan, et al.
Publicado: (2022)

Enhanced LC-ESI-MS/MS Sensitivity by Cationic Derivatization of Organophosphorus Acids
por: Shamai Yamin, Tamar, et al.
Publicado: (2023)

Stability of sample extracts of vitamin D(3) metabolites after chemical derivatization for LC–MS/MS analysis
por: Alexandridou, Anastasia, et al.
Publicado: (2022)

Precolumn derivatization LC–MS/MS method for the determination and pharmacokinetic study of glucosamine in human plasma and urine
por: Song, Min, et al.
Publicado: (2012)

Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS
por: Shih, Ying-Ming, et al.
Publicado: (2018)

Quantification of Cellular Folate Species by LC-MS after Stabilization by Derivatization
por: Schittmayer, Matthias, et al.
Publicado: (2018)

Metabolomics of Clinical Poisoning by Aconitum Alkaloids Using Derivatization LC-MS
por: Zhang, Yida, et al.
Publicado: (2019)

Targeted LC–MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA
por: Eggink, Mark, et al.
Publicado: (2010)

In Matrix Derivatization Combined with LC-MS/MS Results in Ultrasensitive Quantification of Plasma Free Metanephrines and Catecholamines
por: van Faassen, Martijn, et al.
Publicado: (2020)

Comparing derivatization reagents for quantitative LC–MS/MS analysis of a variety of vitamin D metabolites
por: Alexandridou, Anastasia, et al.
Publicado: (2023)

Sensitive and rapid determination of amantadine without derivatization in human plasma by LC–MS/MS for a bioequivalence study
por: Bhadoriya, Abhaysingh, et al.
Publicado: (2018)

MTBSTFA derivatization-LC-MS/MS approach for the quantitative analysis of endogenous nucleotides in human colorectal carcinoma cells
por: Zhang, Huixia, et al.
Publicado: (2022)

Dispersive Solid–Liquid Extraction Coupled with LC-MS/MS for the Determination of Sulfonylurea Herbicides in Strawberries
por: Song, Nho-Eul, et al.
Publicado: (2019)

Determination of Dodecanol and Short-Chained Ethoxylated Dodecanols by LC–MS/MS (with Electrospray Ionization) After Their Derivatization (with Phenyl Isocyanate)
por: Zembrzuska, Joanna
Publicado: (2017)

Development and Verification of a Precolumn Derivatization LC-MS/MS Method for the Pharmacokinetic Study of Houttuynine of Houttuynia Essential Oil
por: Liu, Yuanyuan, et al.
Publicado: (2021)

ODP179 Development of Derivatization-free ID-LC/MS/MS Method for Simultaneous Measurement of Human Serum Monosaccharides
por: Tse, Chui, et al.
Publicado: (2022)

Derivatization of Methylglyoxal for LC-ESI-MS Analysis—Stability and Relative Sensitivity of Different Derivatives
por: Fritzsche, Stefan, et al.
Publicado: (2018)

Coupling functionalized cobalt ferrite nanoparticle enrichment with online LC/MS/MS for top-down phosphoproteomics
por: Chen, Bifan, et al.
Publicado: (2017)

Determination of ergocalciferol in human plasma after Diels-Alder derivatization by LC–MS/MS and its application to a bioequivalence study
por: Contractor, Pritesh, et al.
Publicado: (2017)

Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag(+)CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: Increased Levels and Association with Disability during Acute Attack
por: Cha, Eunju, et al.
Publicado: (2016)

2-Hydrazinoquinoline as a Derivatization Agent for LC-MS-Based Metabolomic Investigation of Diabetic Ketoacidosis
por: Lu, Yuwei, et al.
Publicado: (2013)

Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization
por: Gamon, Luke F., et al.
Publicado: (2020)

Detection of Podocin in Human Urine Sediment Samples by Charge Derivatization and LC-MS-MRM Method
por: Bąchor, Remigiusz, et al.
Publicado: (2020)

A Practical Method for Amino Acid Analysis by LC-MS Using Precolumn Derivatization with Urea
por: Zhao, Runjin, et al.
Publicado: (2023)

GC-MS/MS Determination of Steroid Hormones in Urine Using Solid-Phase Derivatization as an Alternative to Conventional Methods
por: Temerdashev, Azamat, et al.
Publicado: (2022)

2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites
por: Alexandridou, Anastasia, et al.
Publicado: (2023)

Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine(†)
por: Bhamra, Inder, et al.
Publicado: (2012)

Organization of GC/MS and LC/MS metabolomics data into chemical libraries
por: DeHaven, Corey D, et al.
Publicado: (2010)

LC-MS/MS Quantification of Tramadol and Gabapentin Utilizing Solid Phase Extraction
por: Nagaraju, Pappula, et al.
Publicado: (2018)

Novel Microcystins from Planktothrix prolifica NIVA-CYA 544 Identified by LC-MS/MS, Functional Group Derivatization and (15)N-labeling
por: Mallia, Vittoria, et al.
Publicado: (2019)

A novel LC-MS/MS method combined with derivatization for simultaneous quantification of vitamin D metabolites in human serum with diabetes as well as hyperlipidemia
por: Wang, Xiaodi, et al.
Publicado: (2023)

Integrated LC-MS metabolomics with dual derivatization for quantification of FFAs in fecal samples of hepatocellular carcinoma patients
por: Zhang, Jiangang, et al.
Publicado: (2021)

LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine
por: Tiwari, Ravi N., et al.
Publicado: (2015)

Dhb Microcystins Discovered in USA Using an Online Concentration LC–MS/MS Platform
por: Birbeck, Johnna A., et al.
Publicado: (2019)

Ion-Pairing Chromatography and Amine Derivatization Provide Complementary Approaches for the Targeted LC-MS Analysis of the Polar Metabolome
por: Sagi-Kiss, Virag, et al.
Publicado: (2022)

Liquid Chromatography-Mass Spectrometry (LC-MS) Derivatization-Based Methods for the Determination of Fatty Acids in Biological Samples
por: Mantzourani, Christiana, et al.
Publicado: (2022)

Fecal metabolite analysis of Japanese macaques in Yakushima by LC-MS/MS and LC-QTOF-MS
por: TSUCHIDA, Sayaka, et al.
Publicado: (2021)

Determination of Organophosphorus Esters in Fall Protection Equipment by Accelerated Solvent Extraction and Solid-Phase Extraction Coupled with LC-MS/MS Detection
por: Li, Haihong, et al.
Publicado: (2021)

MALDI-TOF MS Analysis of Native and Permethylated or Benzimidazole-Derivatized Polysaccharides
por: Hung, Wei-Ting, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vvk1me8j6vhnlp8llsbiao6bpb