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Wedelolactone Enhances Osteoblastogenesis through ERK- and JNK-mediated BMP2 Expression and Smad/1/5/8 Phosphorylation

Our previous study showed that wedelolactone, a compound isolated from Ecliptae herba, has the potential to enhance osteoblastogenesis. However, the molecular mechanisms by which wedelolactone promoted osteoblastogenesis from bone marrow mesenchymal stem cells (BMSCs) remain largely unknown. In this...

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Detalles Bibliográficos
Autores principales: Zhu, Di, Deng, Xue, Han, Xiao-Fei, Sun, Xiao-Xin, Pan, Tao-Wen, Zheng, Lu-Ping, Liu, Yan-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017959/
https://www.ncbi.nlm.nih.gov/pubmed/29498687
http://dx.doi.org/10.3390/molecules23030561