Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone

Sauchinone, an active lignan isolated from the aerial parts of Saururus chinensis (Saururaceae), exhibits anti-inflammatory, anti-obesity, anti-hyperglycemic, and anti-hepatic steatosis effects. As herb–drug interaction (HDI) through cytochrome P450s (CYPs)-mediated metabolism limits clinical applic...

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Detalles Bibliográficos
Autores principales: Gong, Eun Chae, Chea, Satya, Balupuri, Anand, Kang, Nam Sook, Chin, Young-Won, Choi, Young Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017976/
https://www.ncbi.nlm.nih.gov/pubmed/29498658
http://dx.doi.org/10.3390/molecules23030555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017976/
https://www.ncbi.nlm.nih.gov/pubmed/29498658
http://dx.doi.org/10.3390/molecules23030555

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