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Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone
Sauchinone, an active lignan isolated from the aerial parts of Saururus chinensis (Saururaceae), exhibits anti-inflammatory, anti-obesity, anti-hyperglycemic, and anti-hepatic steatosis effects. As herb–drug interaction (HDI) through cytochrome P450s (CYPs)-mediated metabolism limits clinical applic...
Autores principales: | Gong, Eun Chae, Chea, Satya, Balupuri, Anand, Kang, Nam Sook, Chin, Young-Won, Choi, Young Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017976/ https://www.ncbi.nlm.nih.gov/pubmed/29498658 http://dx.doi.org/10.3390/molecules23030555 |
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