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Web Tool for Navigating and Plotting SomaLogic ADAT Files

SOMAscan™ is a complex proteomic platform created by SomaLogic. Experimental data resulting from the assay is provided by SomaLogic in a proprietary text-based format called ADAT. This manuscript describes a user-friendly point and click open source, platform-independent software tool designed to be...

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Detalles Bibliográficos
Autores principales: Cheung, Foo, Fantoni, Giovanna, Conner, Maria, Sellers, Brian A, Kotliarov, Yuri, Candia, Julián, Stagliano, Katherine, Biancotto, Angélique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017986/
https://www.ncbi.nlm.nih.gov/pubmed/29951204
http://dx.doi.org/10.5334/jors.166
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author Cheung, Foo
Fantoni, Giovanna
Conner, Maria
Sellers, Brian A
Kotliarov, Yuri
Candia, Julián
Stagliano, Katherine
Biancotto, Angélique
author_facet Cheung, Foo
Fantoni, Giovanna
Conner, Maria
Sellers, Brian A
Kotliarov, Yuri
Candia, Julián
Stagliano, Katherine
Biancotto, Angélique
author_sort Cheung, Foo
collection PubMed
description SOMAscan™ is a complex proteomic platform created by SomaLogic. Experimental data resulting from the assay is provided by SomaLogic in a proprietary text-based format called ADAT. This manuscript describes a user-friendly point and click open source, platform-independent software tool designed to be used for navigating and plotting data from an ADAT file. This tool was used either alone or in conjunction with other tools as a first pass analysis of the data on several different on-going research projects. We have seen a need from our experience for a web interface to the ADAT file so that users can navigate, generate plots, perform QC and conduct statistical analysis on their own data in a point and click manner. After several rounds of interacting with biologists and their requirements with respect to data analysis, we present an online interactive Shiny Web Tool for Navigating and Plotting data contained within the ADAT file. Extensive video tutorials, example data, the tool and the source code are available online.
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spelling pubmed-60179862018-06-25 Web Tool for Navigating and Plotting SomaLogic ADAT Files Cheung, Foo Fantoni, Giovanna Conner, Maria Sellers, Brian A Kotliarov, Yuri Candia, Julián Stagliano, Katherine Biancotto, Angélique J Open Res Softw Article SOMAscan™ is a complex proteomic platform created by SomaLogic. Experimental data resulting from the assay is provided by SomaLogic in a proprietary text-based format called ADAT. This manuscript describes a user-friendly point and click open source, platform-independent software tool designed to be used for navigating and plotting data from an ADAT file. This tool was used either alone or in conjunction with other tools as a first pass analysis of the data on several different on-going research projects. We have seen a need from our experience for a web interface to the ADAT file so that users can navigate, generate plots, perform QC and conduct statistical analysis on their own data in a point and click manner. After several rounds of interacting with biologists and their requirements with respect to data analysis, we present an online interactive Shiny Web Tool for Navigating and Plotting data contained within the ADAT file. Extensive video tutorials, example data, the tool and the source code are available online. 2017-09-08 2017 /pmc/articles/PMC6017986/ /pubmed/29951204 http://dx.doi.org/10.5334/jors.166 Text en This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Cheung, Foo
Fantoni, Giovanna
Conner, Maria
Sellers, Brian A
Kotliarov, Yuri
Candia, Julián
Stagliano, Katherine
Biancotto, Angélique
Web Tool for Navigating and Plotting SomaLogic ADAT Files
title Web Tool for Navigating and Plotting SomaLogic ADAT Files
title_full Web Tool for Navigating and Plotting SomaLogic ADAT Files
title_fullStr Web Tool for Navigating and Plotting SomaLogic ADAT Files
title_full_unstemmed Web Tool for Navigating and Plotting SomaLogic ADAT Files
title_short Web Tool for Navigating and Plotting SomaLogic ADAT Files
title_sort web tool for navigating and plotting somalogic adat files
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017986/
https://www.ncbi.nlm.nih.gov/pubmed/29951204
http://dx.doi.org/10.5334/jors.166
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