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Colony and Single Cell Level Analysis of the Heterogeneous Response of Cryptococcus neoformans to Fluconazole

Cryptococcus neoformans is a human fungal pathogen that can cause fatal meningitis in immunocompromised individuals. Fluconazole (FLC) is a fungistatic drug administered to treat cryptococcosis. When exposed to the inhibitory concentration of FLC, C. neoformans exhibits heteroresistance where a smal...

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Detalles Bibliográficos
Autores principales:	Altamirano, Sophie, Simmons, Charles, Kozubowski, Lukasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018158/ https://www.ncbi.nlm.nih.gov/pubmed/29971221 http://dx.doi.org/10.3389/fcimb.2018.00203

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