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Stimulation of the Internal Ribosome Entry Site (IRES)-Dependent Translation of Enterovirus 71 by DDX3X RNA Helicase and Viral 2A and 3C Proteases
The translation of enterovirus 71 (EV71) is mediated by an internal ribosome entry site (IRES)-dependent manner. EV71 IRES comprises five highly structured domains (domains II-VI) in the 5′-untranslated region of the viral mRNA. A conserved AUG triplet residing in domain VI is proposed to be the rib...
Autores principales: | Su, Yu-Siang, Tsai, Ai-Hsuan, Ho, Yueh-Feng, Huang, Shin-Yi, Liu, Yen-Chun, Hwang, Lih-Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018165/ https://www.ncbi.nlm.nih.gov/pubmed/29971060 http://dx.doi.org/10.3389/fmicb.2018.01324 |
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