Cargando…

Combination Therapy for Multi-Target Manipulation of Secondary Brain Injury Mechanisms

Traumatic brain injury (TBI) is a major healthcare problem that affects millions of people worldwide. Despite advances in understanding and developing preventative and treatment strategies using preclinical animal models, clinical trials to date have failed, and a 'magic bullet’ for effectively...

Descripción completa

Detalles Bibliográficos
Autores principales:	Somayaji, Mahadevabharath R., Przekwas, Andrzej J., Gupta, Raj K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018188/ https://www.ncbi.nlm.nih.gov/pubmed/28847295 http://dx.doi.org/10.2174/1570159X15666170828165711

Ejemplares similares

Synaptic Mechanisms of Blast-Induced Brain Injury
por: Przekwas, Andrzej, et al.
Publicado: (2016)

Mathematical Models of Blast-Induced TBI: Current Status, Challenges, and Prospects
por: Gupta, Raj K., et al.
Publicado: (2013)

Mathematical model of mechanobiology of acute and repeated synaptic injury and systemic biomarker kinetics
por: Gharahi, Hamidreza, et al.
Publicado: (2023)

Washing hands and the face may reduce COVID-19 infection
por: Przekwas, Andrzej, et al.
Publicado: (2020)

Mitochondria: Novel Mechanisms and Therapeutic Targets for Secondary Brain Injury After Intracerebral Hemorrhage
por: Chen, Weixiang, et al.
Publicado: (2021)

A Review of Traumatic Brain Injury and the Gut Microbiome: Insights into Novel Mechanisms of Secondary Brain Injury and Promising Targets for Neuroprotection
por: Zhu, Caroline S., et al.
Publicado: (2018)

Mechanically manipulating glymphatic transport by ultrasound combined with microbubbles
por: Ye, Dezhuang, et al.
Publicado: (2023)

Manipulating Brains
por: Walsh, Vincent, et al.
Publicado: (2006)

Multi-Mechanistic Approaches to the Treatment of Traumatic Brain Injury: A Review
por: Lynch, Daniel G., et al.
Publicado: (2023)

Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury
por: Shultz, Robert B., et al.
Publicado: (2017)

Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage
por: Bautista, Wendy, et al.
Publicado: (2021)

Do blast induced skull flexures result in axonal deformation?
por: Garimella, Harsha T., et al.
Publicado: (2018)

Emergence of the Wallerian degeneration pathway as a mechanism of secondary brain injury
por: Hill, Ciaran Scott, et al.
Publicado: (2020)

Brain-targeted drug delivery by manipulating protein corona functions
por: Zhang, Zui, et al.
Publicado: (2019)

Combined Therapy Potential of Apocynin and Tert-butylhydroquinone as a Therapeutic Agent to Prevent Secondary Progression to Traumatic Brain Injury
por: Parastan, Rovie Hikari, et al.
Publicado: (2020)

Apelin-13 as a novel target for intervention in secondary injury after traumatic brain injury
por: Bao, Hai-jun, et al.
Publicado: (2016)

Cerebrospinal fluid leak secondary to chiropractic manipulation
por: Kusnezov, Nicholas A., et al.
Publicado: (2013)

Microglial pyroptosis: Therapeutic target in secondary brain injury following intracerebral hemorrhage
por: Gu, Lingui, et al.
Publicado: (2022)

Tackling Neuroinflammation After Traumatic Brain Injury: Complement Inhibition as a Therapy for Secondary Injury
por: van Erp, Inge A. M., et al.
Publicado: (2022)

Antisense-Mediated RNA Targeting: Versatile and Expedient Genetic Manipulation in the Brain
por: Zalachoras, Ioannis, et al.
Publicado: (2011)

Evaluating Drug Deposition Patterns from Turbuhaler® in Healthy and Diseased Lung Models of Preschool Children
por: Kannan, Ravishekar, et al.
Publicado: (2022)

Changes of Noradrenaline in Brain Homogenate of Rats with Brain Injury Secondary to Intracerebral Hemorrhage: A Study of the Mechanism
por: Xu, Zhi-Qiang, et al.
Publicado: (2005)

Brain: biomedical knowledge manipulation
por: Croset, Samuel, et al.
Publicado: (2013)

Early DNase-I therapy delays secondary brain damage after traumatic brain injury in adult mice
por: Krämer, Tobias J., et al.
Publicado: (2023)

Dysbiosis in the Development of Type I Diabetes and Associated Complications: From Mechanisms to Targeted Gut Microbes Manipulation Therapies
por: Gradisteanu Pircalabioru, Gratiela, et al.
Publicado: (2021)

Experimental Manipulations to Test Theory-Driven Mechanisms of Cognitive Behavior Therapy
por: Southward, Matthew W., et al.
Publicado: (2020)

Manipulating extracellular tumour pH: an effective target for cancer therapy
por: Hao, Guanyu, et al.
Publicado: (2018)

Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior
por: Vu, Mai-Anh T., et al.
Publicado: (2023)

Singular configurations of mechanisms and manipulators
por: Müller, Andreas, et al.
Publicado: (2019)

Managing traumatic brain injury secondary to explosions
por: Burgess, Paula, et al.
Publicado: (2010)

Traumatic Brain Injury and Secondary Neurodegenerative Disease
por: Dodd, William S., et al.
Publicado: (2022)

Spinal Accessory Nerve Injury Induced by Manipulation Therapy: A Case Report
por: Yoon, Jung Ro, et al.
Publicado: (2018)

Inducible and combinatorial gene manipulation in mouse brain
por: Dogbevia, Godwin K., et al.
Publicado: (2015)

Secondary Eating Disorder: A Reality? Case Report of Post Brain Injury Sequelae
por: Das, Aparna, et al.
Publicado: (2017)

Mitochondria-Targeted Antioxidants as Potential Therapy for the Treatment of Traumatic Brain Injury
por: Stelmashook, Elena V., et al.
Publicado: (2019)

A Comparative Evaluation of Desoximetasone Cream and Ointment Formulations Using Experiments and In Silico Modeling
por: Matharoo, Namrata S., et al.
Publicado: (2023)

Effects and mechanisms of CTRP3 overexpression in secondary brain injury following intracerebral hemorrhage in rats
por: Wan, Yu, et al.
Publicado: (2022)

Controlled and localized genetic manipulation in the brain
por: Aronoff, Rachel, et al.
Publicado: (2006)

Manipulation of fungal development as source of novel secondary metabolites for biotechnology
por: Gerke, Jennifer, et al.
Publicado: (2014)

Death by Disimpaction: A Bradycardic Arrest Secondary to Rectal Manipulation
por: Sampson, Christopher S., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1tjsl4id12lufcti21mgitlngv