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Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia

Tolerance to antifungal drug concentrations above the minimal inhibitory concentration (MIC) is rarely quantified, and current clinical recommendations suggest it should be ignored. Here, we quantify antifungal tolerance in Candida albicans isolates as the fraction of growth above the MIC, and find...

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Detalles Bibliográficos
Autores principales:	Rosenberg, Alexander, Ene, Iuliana V., Bibi, Maayan, Zakin, Shiri, Segal, Ella Shtifman, Ziv, Naomi, Dahan, Alon M., Colombo, Arnaldo Lopes, Bennett, Richard J., Berman, Judith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018213/ https://www.ncbi.nlm.nih.gov/pubmed/29941885 http://dx.doi.org/10.1038/s41467-018-04926-x

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