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Osteoarthritis-Like Changes in Bardet–Biedl Syndrome Mutant Ciliopathy Mice (Bbs1(M390R/M390R)): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation
Osteoarthritis (OA) is a debilitating inflammation related disease characterized by joint pain and effusion, loss of mobility, and deformity that may result in functional joint failure and significant impact on quality of life. Once thought of as a simple “wear and tear” disease, it is now widely re...
Autores principales: | Sheffield, Isaac D., McGee, Mercedes A., Glenn, Steven J., Baek, Da Young, Coleman, Joshua M., Dorius, Bradley K., Williams, Channing, Rose, Brandon J., Sanchez, Anthony E., Goodman, Michael A., Daines, John M., Eggett, Dennis L., Sheffield, Val C., Suli, Arminda, Kooyman, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018413/ https://www.ncbi.nlm.nih.gov/pubmed/29971011 http://dx.doi.org/10.3389/fphys.2018.00708 |
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