NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson’s Disease

Na(+)-Ca(2+) exchanger (NCX) isoforms constitute the major cellular Ca(2+) extruding system in neurons and microglia. We herein investigated the role of NCX isoforms in the pathophysiology of Parkinson’s disease (PD). Their expression and activity were evaluated in neurons and glia of mice expressin...

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Detalles Bibliográficos
Autores principales: Sirabella, Rossana, Sisalli, Maria Josè, Costa, Giulia, Omura, Katia, Ianniello, Gaetano, Pinna, Annalisa, Morelli, Micaela, Di Renzo, Gianfranco Maria, Annunziato, Lucio, Scorziello, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018508/
https://www.ncbi.nlm.nih.gov/pubmed/29941946
http://dx.doi.org/10.1038/s41419-018-0775-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018508/
https://www.ncbi.nlm.nih.gov/pubmed/29941946
http://dx.doi.org/10.1038/s41419-018-0775-7

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