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The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery
P. aeruginosa causes a substantial number of nosocomial infections and is the leading cause of death of cystic fibrosis patients. This Gram-negative bacterium is highly resistant against antibiotics and further protects itself by forming a biofilm. Moreover, a high genomic variability among clinical...
Autores principales: | Sommer, Roman, Wagner, Stefanie, Varrot, Annabelle, Nycholat, Corwin M., Khaledi, Ariane, Häussler, Susanne, Paulson, James C., Imberty, Anne, Titz, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018602/ https://www.ncbi.nlm.nih.gov/pubmed/30155149 http://dx.doi.org/10.1039/c6sc00696e |
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