SURF1 knockout cloned pigs: Early onset of a severe lethal phenotype

Leigh syndrome (LS) associated with cytochrome c oxidase (COX) deficiency is an early onset, fatal mitochondrial encephalopathy, leading to multiple neurological failure and eventually death, usually in the first decade of life. Mutations in SURF1, a nuclear gene encoding a mitochondrial protein inv...

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Detalles Bibliográficos
Autores principales: Quadalti, C., Brunetti, D., Lagutina, I., Duchi, R., Perota, A., Lazzari, G., Cerutti, R., Di Meo, I., Johnson, M., Bottani, E., Crociara, P., Corona, C., Grifoni, S., Tiranti, V., Fernandez-Vizarra, E., Robinson, A.J., Viscomi, C., Casalone, C., Zeviani, M., Galli, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018622/
https://www.ncbi.nlm.nih.gov/pubmed/29601977
http://dx.doi.org/10.1016/j.bbadis.2018.03.021

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