Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB

Transient receptor potential (TRP) channels are involved in various physiological processes, including sensory transduction. The TRP channel TRPV6 mediates calcium uptake in epithelia and its expression is dramatically increased in numerous types of cancer. TRPV6 inhibitors suppress tumor growth, bu...

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Detalles Bibliográficos
Autores principales: Singh, Appu K., Saotome, Kei, McGoldrick, Luke L., Sobolevsky, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018633/
https://www.ncbi.nlm.nih.gov/pubmed/29941865
http://dx.doi.org/10.1038/s41467-018-04828-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018633/
https://www.ncbi.nlm.nih.gov/pubmed/29941865
http://dx.doi.org/10.1038/s41467-018-04828-y

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