C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway

The mechanisms that connect complement system activation and basal deposit formation in early stages of age-related macular degeneration (AMD) are insufficiently understood, which complicates the design of efficient therapies to prevent disease progression. Using human fetal (hf) retinal pigment epi...

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Detalles Bibliográficos
Autores principales: Fernandez-Godino, Rosario, Pierce, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018664/
https://www.ncbi.nlm.nih.gov/pubmed/29946065
http://dx.doi.org/10.1038/s41598-018-28143-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018664/
https://www.ncbi.nlm.nih.gov/pubmed/29946065
http://dx.doi.org/10.1038/s41598-018-28143-0

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