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Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography

Inflammation plays an important role in the development of atherosclerosis and its complications. Because the folate receptor β (FR-β) is selectively expressed on macrophages, an FR targeted imaging agent could be useful for assessment of atherosclerotic inflammation. We investigated aluminum fluori...

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Detalles Bibliográficos
Autores principales: Silvola, Johanna M. U., Li, Xiang-Guo, Virta, Jenni, Marjamäki, Päivi, Liljenbäck, Heidi, Hytönen, Jarkko P., Tarkia, Miikka, Saunavaara, Virva, Hurme, Saija, Palani, Senthil, Hakovirta, Harri, Ylä-Herttuala, Seppo, Saukko, Pekka, Chen, Qingshou, Low, Philip S., Knuuti, Juhani, Saraste, Antti, Roivainen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018703/
https://www.ncbi.nlm.nih.gov/pubmed/29946129
http://dx.doi.org/10.1038/s41598-018-27618-4