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Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography
Inflammation plays an important role in the development of atherosclerosis and its complications. Because the folate receptor β (FR-β) is selectively expressed on macrophages, an FR targeted imaging agent could be useful for assessment of atherosclerotic inflammation. We investigated aluminum fluori...
Autores principales: | Silvola, Johanna M. U., Li, Xiang-Guo, Virta, Jenni, Marjamäki, Päivi, Liljenbäck, Heidi, Hytönen, Jarkko P., Tarkia, Miikka, Saunavaara, Virva, Hurme, Saija, Palani, Senthil, Hakovirta, Harri, Ylä-Herttuala, Seppo, Saukko, Pekka, Chen, Qingshou, Low, Philip S., Knuuti, Juhani, Saraste, Antti, Roivainen, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018703/ https://www.ncbi.nlm.nih.gov/pubmed/29946129 http://dx.doi.org/10.1038/s41598-018-27618-4 |
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