S-nitrosation of protein phosphatase 1 mediates alcohol-induced ciliary dysfunction

Alcohol use disorder (AUD) is a strong risk factor for development and mortality of pneumonia. Mucociliary clearance, a key innate defense against pneumonia, is perturbed by alcohol use. Specifically, ciliated airway cells lose the ability to increase ciliary beat frequency (CBF) to β-agonist stimul...

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Detalles Bibliográficos
Autores principales: Price, Michael E., Case, Adam J., Pavlik, Jacqueline A., DeVasure, Jane M., Wyatt, Todd A., Zimmerman, Matthew C., Sisson, Joseph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018795/
https://www.ncbi.nlm.nih.gov/pubmed/29946131
http://dx.doi.org/10.1038/s41598-018-27924-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018795/
https://www.ncbi.nlm.nih.gov/pubmed/29946131
http://dx.doi.org/10.1038/s41598-018-27924-x

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