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Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia

Genome sequences of 247 Plasmodium falciparum isolates collected in The Gambia in 2008 and 2014 were analysed to identify changes possibly related to the scale-up of antimalarial interventions that occurred during this period. Overall, there were 15 regions across the genomes with signatures of posi...

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Detalles Bibliográficos
Autores principales: Amambua-Ngwa, Alfred, Jeffries, David, Amato, Roberto, Worwui, Archibald, Karim, Mane, Ceesay, Sukai, Nyang, Haddy, Nwakanma, Davis, Okebe, Joseph, Kwiatkowski, Dominic, Conway, David J., D’Alessandro, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018809/
https://www.ncbi.nlm.nih.gov/pubmed/29946063
http://dx.doi.org/10.1038/s41598-018-28017-5