Cargando…

Serine/threonine phosphatase 5 (PP5C/PPP5C) regulates the ISOC channel through a PP5C-FKBP51 axis

Pulmonary endothelial cells express a store-operated calcium entry current (I(soc)), which contributes to inter-endothelial cell gap formation. I(soc) is regulated by a heterocomplex of proteins that includes the immunophilin FKBP51. FKBP51 inhibits I(soc) by mechanisms that are not fully understood...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hamilton, Caleb L., Abney, Kevin A., Vasauskas, Audrey A., Alexeyev, Mikhail, Ni, Li, Honkanen, Richard E., Scammell, Jonathan G., Cioffi, Donna L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018905/ https://www.ncbi.nlm.nih.gov/pubmed/29283027 http://dx.doi.org/10.1177/2045893217753156

Ejemplares similares

PP5 (PPP5C) is a phosphatase of Dvl2
por: Xie, Jianlei, et al.
Publicado: (2018)

Protective role of FKBP51 in calcium entry-induced endothelial barrier disruption
por: Hamilton, Caleb L., et al.
Publicado: (2017)

Serine / threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling
por: Dean, David A, et al.
Publicado: (2001)

Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth
por: Loveday, Chey, et al.
Publicado: (2015)

Corrigendum: Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth
por: Loveday, Chey, et al.
Publicado: (2019)

Catalytic activity of a novel serine/threonine protein phosphatase PP5 from Leishmania major
por: Norris-Mullins, Brianna, et al.
Publicado: (2014)

Quantum-based modeling implies that bidentate Arg(89)-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation
por: Salter, E. Alan, et al.
Publicado: (2023)

Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels
por: Bailus, Barbara J., et al.
Publicado: (2021)

Activation of Protein Serine/Threonine Phosphatase PP2Cα Efficiently Prevents Liver Fibrosis
por: Wang, Lirui, et al.
Publicado: (2010)

Growth arrest of PPP2R5C and PPP2R5D double knockout mice indicates a genetic interaction and conserved function for these PP2A B subunits
por: Dyson, Jade J., et al.
Publicado: (2021)

A novel tetratricopeptide repeat (TPR) containing PP5 serine/threonine protein phosphatase in the malaria parasite, Plasmodium falciparum
por: Dobson, Sean, et al.
Publicado: (2001)

A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51
por: O'Leary, John C., et al.
Publicado: (2011)

Screening for serine/threonine kinases phosphorylating Stat5
por: Berger, Angelika, et al.
Publicado: (2011)

Dysregulation of the serine/threonine phosphatase PP2A contributes to autoimmunity
por: Crispín, JC
Publicado: (2012)

A serine/threonine phosphatase, PP2A, controls autoimmunity
por: Tsokos, George C
Publicado: (2014)

Search for B = 2, S = 0 resonances in pp collisions at 5.5 GeV/c
por: Alexander, G, et al.
Publicado: (1965)

Calyculins and Related Marine Natural Products as Serine-Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C
por: Fagerholm, Annika E., et al.
Publicado: (2010)

Expression and distribution of PPP2R5C gene in leukemia
por: Zheng, Haitao, et al.
Publicado: (2011)

PPP6C, a serine-threonine phosphatase, regulates melanocyte differentiation and contributes to melanoma tumorigenesis through modulation of MITF activity
por: Maskin, Carolyn R., et al.
Publicado: (2022)

Strange-particle production in pp collisions at 5.7 GeV/c
por: Atherton, Henry W, et al.
Publicado: (1975)

PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis
por: Cheng, Yong-Sheng, et al.
Publicado: (2015)

Mechanisms of Systolic Cardiac Dysfunction in PP2A, PP5 and PP2AxPP5 Double Transgenic Mice
por: Dörner, Mara-Francine, et al.
Publicado: (2021)

The Sequential Action of MIDA9/PP2C.D1, PP2C.D2, and PP2C.D5 Is Necessary to Form and Maintain the Hook After Germination in the Dark
por: Rovira, Arnau, et al.
Publicado: (2021)

Peripheral production and decay parameters of $N^{*}$ + + (1238) in pp -> n $N^{*}$ + + (1238) at 5.5 GeV/c
por: Alexander, G, et al.
Publicado: (1966)

Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades
por: Smolen, Kali A., et al.
Publicado: (2023)

Characterizing the original anti‐C5 function‐blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5
por: Zelek, Wioleta M., et al.
Publicado: (2020)

Production of Lambda(c) in pp and PbPb collisions at sqrt(s) = 5.02 TeV
por: CMS Collaboration
Publicado: (2019)

\pi \pi scattering effects in pp.bar. annihilations at 2.5 GeV/c
por: Clayton, J, et al.
Publicado: (1968)

Peripheral production of $N^{*}$ (1518) -> p $\pi^{+} \pi^{-}$ and $N^{*}$ (1688) ->p $\pi^{+} \pi^{-}$ resonances in pp -> pp $\pi^{+} \pi^{-}$ reactions at 5.5 GeV/c
por: Alexander, G, et al.
Publicado: (1965)

PP2A subunit PPP2R2C is downregulated in the brains of Alzheimer’s transgenic mice
por: Leong, Waiian, et al.
Publicado: (2020)

Protein Serine/Threonine Phosphatase Type 2C of Leishmania mexicana
por: Escalona-Montaño, Alma Reyna, et al.
Publicado: (2021)

MiR-520a-5p/PPP5C regulation pattern is identified as the key to gemcitabine resistance in pancreatic cancer
por: Fu, Ruibiao, et al.
Publicado: (2022)

Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cells
por: Chen, Ming, et al.
Publicado: (2017)

Overexpression of the PP2A-C5 gene confers increased salt tolerance in Arabidopsis thaliana
por: Hu, Rongbin, et al.
Publicado: (2017)

Draft Genome Sequence of Carbaryl-Degrading Soil Isolate Pseudomonas sp. Strain C5pp
por: Trivedi, Vikas D., et al.
Publicado: (2016)

The Role of Serine-Threonine Protein Phosphatase PP2A in Plant Oxidative Stress Signaling—Facts and Hypotheses
por: Máthé, Csaba, et al.
Publicado: (2019)

The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets
por: Makhoul, Stephanie, et al.
Publicado: (2020)

Regulation of hepatitis C virus replication via threonine phosphorylation of the NS5A protein
por: Goonawardane, Niluka, et al.
Publicado: (2018)

Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer
por: Storebjerg, Tine Maj, et al.
Publicado: (2018)

Dexamethasone Sensitizes Acute Monocytic Leukemia Cells to Ara-C by Upregulating FKBP51
por: Sun, Huanxin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f9iqhvmofq7rfsrqgf177fe1bf