Cargando…

Integrative multi‐omics analysis of intestinal organoid differentiation

Intestinal organoids accurately recapitulate epithelial homeostasis in vivo, thereby representing a powerful in vitro system to investigate lineage specification and cellular differentiation. Here, we applied a multi‐omics framework on stem cell‐enriched and stem cell‐depleted mouse intestinal organ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lindeboom, Rik GH, van Voorthuijsen, Lisa, Oost, Koen C, Rodríguez‐Colman, Maria J, Luna‐Velez, Maria V, Furlan, Cristina, Baraille, Floriane, Jansen, Pascal WTC, Ribeiro, Agnès, Burgering, Boudewijn MT, Snippert, Hugo J, Vermeulen, Michiel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018986/ https://www.ncbi.nlm.nih.gov/pubmed/29945941 http://dx.doi.org/10.15252/msb.20188227

Ejemplares similares

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene
por: Oost, Koen C., et al.
Publicado: (2018)

Protocol to profile the bioenergetics of organoids using Seahorse
por: Ludikhuize, Marlies C., et al.
Publicado: (2021)

Proteomic landscape of the primary somatosensory cortex upon sensory deprivation
por: Kole, Koen, et al.
Publicado: (2017)

Introducing the Stem Cell ASCL2 Reporter STAR into Intestinal Organoids
por: Heinz, Maria C., et al.
Publicado: (2020)

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage
por: Heinz, Maria C., et al.
Publicado: (2022)

The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy
por: Lindeboom, Rik G.H., et al.
Publicado: (2019)

Retinoic acid signaling drives differentiation toward the absorptive lineage in colorectal cancer
por: Wester, Roelof A., et al.
Publicado: (2021)

The dynamic interactome and genomic targets of Polycomb complexes during stem cell differentiation
por: Kloet, Susan L., et al.
Publicado: (2016)

NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells
por: Kloet, Susan L., et al.
Publicado: (2018)

Emerging insights on the role of gasdermins in infection and inflammatory diseases
por: Tang, Lipeng, et al.
Publicado: (2020)

Erratum to: Proteomic landscape of the primary somatosensory cortex upon sensory deprivation
por: Kole, Koen, et al.
Publicado: (2018)

Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs
por: Smits, Arne H., et al.
Publicado: (2014)

Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay
por: Hoek, Tim A., et al.
Publicado: (2019)

The rules and impact of nonsense-mediated mRNA decay in human cancers
por: Lindeboom, Rik G.H., et al.
Publicado: (2016)

FOXOs: masters of the equilibrium
por: Gui, Tianshu, et al.
Publicado: (2021)

Development of bioinformatics and multi-omics analyses in organoids
por: Ha, Doyeon, et al.
Publicado: (2023)

STPP-UP: An alternative method for drug target identification using protein thermal stability
por: Zijlmans, Dick W., et al.
Publicado: (2023)

ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small intestine; a multi-omics study
por: Luna Velez, Maria V, et al.
Publicado: (2023)

An integrated organoid omics map extends modeling potential of kidney disease
por: Lassé, Moritz, et al.
Publicado: (2023)

Chk1 and 14‐3‐3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest
por: Yuan, Ruixue, et al.
Publicado: (2018)

Chicken-derived RSPO1 and WNT3 contribute to maintaining longevity of chicken intestinal organoid cultures
por: Oost, Miriam J., et al.
Publicado: (2022)

CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition
por: Post, Jasmin B., et al.
Publicado: (2019)

Rewiring glucose metabolism improves 5-FU efficacy in p53-deficient/KRAS(G12D) glycolytic colorectal tumors
por: Ludikhuize, Marlies C., et al.
Publicado: (2022)

Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader
por: van Muijlwijk, Guus H., et al.
Publicado: (2021)

Kidney Organoids and Tubuloids
por: Yousef Yengej, Fjodor A., et al.
Publicado: (2020)

Phenotypic landscape of intestinal organoid regeneration
por: Lukonin, Ilya, et al.
Publicado: (2020)

Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation
por: Massafra, Vittoria, et al.
Publicado: (2017)

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening
por: Verissimo, Carla S, et al.
Publicado: (2016)

Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons
por: Rother, Nils, et al.
Publicado: (2020)

The Dynamics of Metabolic Characterization in iPSC-Derived Kidney Organoid Differentiation via a Comparative Omics Approach
por: Wang, Qizheng, et al.
Publicado: (2021)

Human forebrain organoids-based multi-omics analyses reveal PCCB’s regulation on GABAergic system contributing to schizophrenia
por: Zhang, Wendiao, et al.
Publicado: (2023)

The Contribution of Evolutionary Game Theory to Understanding and Treating Cancer
por: Wölfl, Benjamin, et al.
Publicado: (2021)

Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation
por: Dijkstra, Jelmer J., et al.
Publicado: (2022)

Berkchaetoazaphilone B has antimicrobial activity and affects energy metabolism
por: Ouyang, Xudong, et al.
Publicado: (2021)

Human forebrain organoid-based multi-omics analyses of PCCB as a schizophrenia associated gene linked to GABAergic pathways
por: Zhang, Wendiao, et al.
Publicado: (2023)

Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress
por: Menjivar, Nico G., et al.
Publicado: (2023)

Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage
por: Bollen, Yannik, et al.
Publicado: (2022)

The Lipid Raft Component Stomatin Interacts with the Na(+) Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake
por: Appelman, Monique D., et al.
Publicado: (2020)

The influence of short-term complications on the outcomes of total elbow arthroplasty
por: Macken, Arno A., et al.
Publicado: (2021)

Sulfur-Based Ylides in Transition-Metal-Catalysed Processes
por: Neuhaus, James D., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_27tn2mteu0emkhhhl2as6uc2at