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Single-dose oral ciprofloxacin prophylaxis as a response to a meningococcal meningitis epidemic in the African meningitis belt: A 3-arm, open-label, cluster-randomized trial
BACKGROUND: Antibiotic prophylaxis for contacts of meningitis cases is not recommended during outbreaks in the African meningitis belt. We assessed the effectiveness of single-dose oral ciprofloxacin administered to household contacts and in village-wide distributions on the overall attack rate (AR)...
Autores principales: | Coldiron, Matthew E., Assao, Bachir, Page, Anne-Laure, Hitchings, Matt D. T., Alcoba, Gabriel, Ciglenecki, Iza, Langendorf, Céline, Mambula, Christopher, Adehossi, Eric, Sidikou, Fati, Tassiou, Elhadji Ibrahim, De Lastours, Victoire, Grais, Rebecca F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019097/ https://www.ncbi.nlm.nih.gov/pubmed/29944651 http://dx.doi.org/10.1371/journal.pmed.1002593 |
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