Cargando…

Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence

BACKGROUND: Cell therapy for the treatment of intervertebral disc degeneration (IDD) faces serious barriers since tissue-specific adult cells such as nucleus pulposus cells (NPCs) have limited proliferative ability and poor regenerative potential; in addition, it is difficult for exogenous adult ste...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiao-Chuan, Wang, Mao-Sheng, Liu, Wei, Zhong, Cheng-Fan, Deng, Gui-Bin, Luo, Shao-Jian, Huang, Chun-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307/ https://www.ncbi.nlm.nih.gov/pubmed/29941029 http://dx.doi.org/10.1186/s13287-018-0919-9

Ejemplares similares

The Regenerative Potential of Notochordal Cells in a Nucleus Pulposus Explant
por: Arkesteijn, Irene T. M., et al.
Publicado: (2017)

Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell‐Derived Exosomes on the Senescence of Nucleus Pulposus Cells
por: Chen, Chang‐chun, et al.
Publicado: (2020)

Transcriptional profiling of the nucleus pulposus: say yes to notochord
por: Shapiro, Irving M, et al.
Publicado: (2010)

An insight on the N‐glycome of notochordal cell‐rich porcine nucleus pulposus during maturation
por: Günay, Büşra, et al.
Publicado: (2023)

Induction of notochordal differentiation of bone marrow mesenchymal-derived stem cells via the stimulation of notochordal cell-rich nucleus pulposus tissue
por: Li, Defang, et al.
Publicado: (2021)

Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration
por: Richardson, Stephen M., et al.
Publicado: (2017)

Effect of coculturing canine notochordal, nucleus pulposus and mesenchymal stromal cells for intervertebral disc regeneration
por: Arkesteijn, Irene TM, et al.
Publicado: (2015)

CD24 identifies nucleus pulposus progenitors/notochordal cells for disc regeneration
por: Liu, Zhuochao, et al.
Publicado: (2018)

A bovine nucleus pulposus explant culture model
por: Salzer, Elias, et al.
Publicado: (2021)

Loss of HIF-1α in the Notochord Results in Cell Death and Complete Disappearance of the Nucleus Pulposus
por: Merceron, Christophe, et al.
Publicado: (2014)

Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus
por: Peck, Sun H., et al.
Publicado: (2017)

Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus
por: Matta, Ajay, et al.
Publicado: (2017)

Resveratrol attenuates inflammation environment-induced nucleus pulposus cell senescence in vitro
por: Li, Xiaoming, et al.
Publicado: (2019)

Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotype
por: Korecki, Casey L, et al.
Publicado: (2010)

Notochordal-cell derived extracellular vesicles exert regenerative effects on canine and human nucleus pulposus cells
por: Bach, Frances, et al.
Publicado: (2017)

Nucleus Pulposus Cell Conditioned Medium Promotes Mesenchymal Stem Cell Differentiation into Nucleus Pulposus-Like Cells under Hypoxic Conditions
por: Sinkemani, Arjun, et al.
Publicado: (2020)

Senescence of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs
por: Kim, Ki-Won, et al.
Publicado: (2008)

Transformation of resident notochord‐descendent nucleus pulposus cells in mouse injury‐induced fibrotic intervertebral discs
por: Au, Tiffany Y. K., et al.
Publicado: (2020)

N-cadherin attenuates nucleus pulposus cell senescence under high-magnitude compression
por: Niu, Ming, et al.
Publicado: (2018)

Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration
por: Erwin, W Mark, et al.
Publicado: (2011)

Inducing Angiogenesis in the Nucleus Pulposus
por: Damle, Sheela R., et al.
Publicado: (2023)

Modulating Notochordal Differentiation of Human Induced Pluripotent Stem Cells Using Natural Nucleus Pulposus Tissue Matrix
por: Liu, Yongxing, et al.
Publicado: (2014)

Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells
por: Lian, Chengjie, et al.
Publicado: (2017)

Chordoma‐derived cell line U‐CH1‐N recapitulates the biological properties of notochordal nucleus pulposus cells
por: Fujita, Nobuyuki, et al.
Publicado: (2016)

The enigma that is the nucleus pulposus cell: the search goes on
por: Erwin, W Mark
Publicado: (2010)

Cell sources proposed for nucleus pulposus regeneration
por: Williams, Rebecca J., et al.
Publicado: (2021)

Alterations of bovine nucleus pulposus cells with aging
por: Molinos, Maria, et al.
Publicado: (2023)

Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration
por: Xu, Meng, et al.
Publicado: (2022)

Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats
por: Lan, Wei-ren, et al.
Publicado: (2019)

Effect of Compression Loading on Human Nucleus Pulposus-Derived Mesenchymal Stem Cells
por: Liang, Hang, et al.
Publicado: (2018)

The Effect of a Cyclooxygenase 2 Inhibitor on Early Degenerated Human Nucleus Pulposus Explants
por: van Dijk, Bart, et al.
Publicado: (2013)

Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells
por: Purmessur, Devina, et al.
Publicado: (2011)

Effect of High Glucose on Stress-Induced Senescence of Nucleus Pulposus Cells of Adult Rats
por: Kong, Jae-Gwan, et al.
Publicado: (2015)

Rebalance of the Polyamine Metabolism Suppresses Oxidative Stress and Delays Senescence in Nucleus Pulposus Cells
por: Che, Hui, et al.
Publicado: (2022)

PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells
por: Zhang, Zhenlei, et al.
Publicado: (2022)

Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats
por: Wang, Jianle, et al.
Publicado: (2018)

Taurine attenuates ER stress-associated apoptosis and catabolism in nucleus pulposus cells
por: Yang, Liuxie, et al.
Publicado: (2022)

Influence of simvastatin on the biological behavior of nucleus pulposus-derived mesenchymal stem cells
por: Huang, Zenan, et al.
Publicado: (2019)

Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration
por: Krouwels, Anita, et al.
Publicado: (2020)

Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo
por: Chen, Deheng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_82r345fhlnrdb2vlkh8lnvtit1