A Mycobacterium avium subsp. paratuberculosis relA deletion mutant and a 35 kDa major membrane protein elicit development of cytotoxic T lymphocytes with ability to kill intracellular bacteria

Efforts to develop live attenuated vaccines against Mycobacterium avium subspecies paratuberculosis (Map), using indirect methods to screen Map deletion mutants for potential efficacy, have not been successful. A reduction in the capacity to survive in macrophages has not predicted the ability of mu...

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Detalles Bibliográficos
Autores principales: Abdellrazeq, Gaber S., Elnaggar, Mahmoud M., Bannantine, John P., Park, Kun T., Souza, Cleverson D., Backer, Brian, Hulubei, Victoria, Fry, Lindsay M., Khaliel, Samy A., Torky, Helmy A., Schneider, David A., Davis, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019527/
https://www.ncbi.nlm.nih.gov/pubmed/29941017
http://dx.doi.org/10.1186/s13567-018-0549-3

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