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Exploring the role of NCCR variation on JC polyomavirus expression from dual reporter minicircles

JC virus (JCV), a ubiquitous human polyomavirus, can cause fatal progressive multifocal leukoencephalopathy (PML) in immune compromised patients. The viral genome is composed of two conserved coding regions separated by a highly variable non-coding control region (NCCR). We analyzed the NCCR sequenc...

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Detalles Bibliográficos
Autores principales: L’Honneur, Anne-Sophie, Leh, Hervé, Laurent-Tchenio, Fanny, Hazan, Uriel, Rozenberg, Flore, Bury-Moné, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019678/
https://www.ncbi.nlm.nih.gov/pubmed/29944671
http://dx.doi.org/10.1371/journal.pone.0199171

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