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Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios
BACKGROUND: The adaptive immune response intrinsically depends on hypervariable human leukocyte antigen (HLA) genes. Concomitantly, correct HLA phenotyping is crucial for successful donor-patient matching in organ transplantation. The cost and technical limitations of current laboratory techniques,...
Autores principales: | Matey-Hernandez, Maria Luisa, Brunak, Søren, Izarzugaza, Jose M. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019707/ https://www.ncbi.nlm.nih.gov/pubmed/29940840 http://dx.doi.org/10.1186/s12859-018-2239-6 |
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