Cargando…

Non-random Mis-segregation of Human Chromosomes

A common assumption is that human chromosomes carry equal chances of mis-segregation during compromised cell division. Human chromosomes vary in multiple parameters that might generate bias, but technological limitations have precluded a comprehensive analysis of chromosome-specific aneuploidy. Here...

Descripción completa

Detalles Bibliográficos
Autores principales:	Worrall, Joseph Thomas, Tamura, Naoka, Mazzagatti, Alice, Shaikh, Nadeem, van Lingen, Tineke, Bakker, Bjorn, Spierings, Diana Carolina Johanna, Vladimirou, Elina, Foijer, Floris, McClelland, Sarah Elizabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019738/ https://www.ncbi.nlm.nih.gov/pubmed/29898405 http://dx.doi.org/10.1016/j.celrep.2018.05.047

Ejemplares similares

Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses
por: Shaikh, Nadeem, et al.
Publicado: (2022)

Short-term molecular consequences of chromosome mis-segregation for genome stability
por: Garribba, Lorenza, et al.
Publicado: (2023)

A kinesin‐based approach for inducing chromosome‐specific mis‐segregation in human cells
por: Truong, My Anh, et al.
Publicado: (2023)

Targeted assembly of ectopic kinetochores to induce chromosome‐specific segmental aneuploidies
por: Tovini, Laura, et al.
Publicado: (2023)

Chromosome mis-segregation and cytokinesis failure in trisomic human cells
por: Nicholson, Joshua M, et al.
Publicado: (2015)

Nuclear chromosome locations dictate segregation error frequencies
por: Klaasen, Sjoerd J., et al.
Publicado: (2022)

The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation
por: Kline, Susan L., et al.
Publicado: (2006)

Centrosome age regulates kinetochore–microtubule stability and biases chromosome mis-segregation
por: Gasic, Ivana, et al.
Publicado: (2015)

Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells
por: Silkworth, William T., et al.
Publicado: (2009)

The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability
por: Hintzen, Dorine C., et al.
Publicado: (2022)

Tumor-Specific Chromosome Mis-Segregation Controls Cancer Plasticity by Maintaining Tumor Heterogeneity
por: Hu, Yuanjie, et al.
Publicado: (2013)

Mild replication stress causes chromosome mis-segregation via premature centriole disengagement
por: Wilhelm, Therese, et al.
Publicado: (2019)

Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells
por: Lauriola, Angela, et al.
Publicado: (2020)

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum
por: Bočkaj, Irena, et al.
Publicado: (2022)

Satellite DNA at the Centromere Is Dispensable for Segregation Fidelity
por: Roberti, Annalisa, et al.
Publicado: (2019)

How Chromosome Mis-Segregation Leads to Cancer: Lessons from BubR1 Mouse Models
por: Lee, Hyunsook
Publicado: (2014)

Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor
por: Quevedo, Rene, et al.
Publicado: (2020)

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient cancer cells
por: Schoonen, Pepijn M., et al.
Publicado: (2019)

Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability
por: Dale, Katie L., et al.
Publicado: (2022)

Alzheimer Aβ Peptide Induces Chromosome Mis-Segregation and Aneuploidy, Including Trisomy 21: Requirement for Tau and APP
por: Granic, Antoneta, et al.
Publicado: (2010)

Beyond Trisomy 21: Phenotypic Variability in People with Down Syndrome Explained by Further Chromosome Mis-segregation and Mosaic Aneuploidy
por: Potter, Huntington
Publicado: (2016)

Spore-autonomous fluorescent protein expression identifies meiotic chromosome mis-segregation as the principal cause of hybrid sterility in yeast
por: Rogers, David W., et al.
Publicado: (2018)

The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
por: Hong, Christy, et al.
Publicado: (2019)

Probing microtubule polymerisation state at single kinetochores during metaphase chromosome motion
por: Armond, Jonathan W., et al.
Publicado: (2015)

Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability
por: Vanhaesebroeck, Bart, et al.
Publicado: (2019)

Cohesin and chromosome segregation
por: Makrantoni, Vasso, et al.
Publicado: (2018)

Unrestrained Spindle Elongation during Recovery from Spindle Checkpoint Activation in cdc15-2 Cells Results in Mis-Segregation of Chromosomes
por: Chai, Chuan Chung, et al.
Publicado: (2010)

Mitotic Spindle Defects and Chromosome Mis-Segregation Induced by LDL/Cholesterol—Implications for Niemann-Pick C1, Alzheimer’s Disease, and Atherosclerosis
por: Granic, Antoneta, et al.
Publicado: (2013)

Chromosomal instability and inflammation: a catch-22 for cancer cells
por: van den Brink, Anouk, et al.
Publicado: (2023)

TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes
por: Shrestha, Roshan L., et al.
Publicado: (2014)

TELOPHASE SEGREGATION OF CHROMOSOMES AND AMITOSIS
por: Molè-Bajer, J.
Publicado: (1965)

For chromosomes, equality means segregation
por: Leslie, Mitch
Publicado: (2009)

Chromosome Segregation: Disarming the Protector
por: Sanyal, Swastika, et al.
Publicado: (2013)

Chromosome segregation in plant meiosis
por: Zamariola, Linda, et al.
Publicado: (2014)

Ensuring fidelity of chromosome segregation
por: Ünal, Elçin, et al.
Publicado: (2018)

Spindle mechanics and chromosome segregation
por: Tolić, Iva M., et al.
Publicado: (2019)

Mechanical Mechanisms of Chromosome Segregation
por: Anjur-Dietrich, Maya I., et al.
Publicado: (2021)

Mechanisms for Chromosome Segregation in Bacteria
por: Gogou, Christos, et al.
Publicado: (2021)

Double-checking chromosome segregation
por: Maiato, Helder, et al.
Publicado: (2023)

Mal3 is a multi-copy suppressor of the sensitivity to microtubule-depolymerizing drugs and chromosome mis-segregation in a fission yeast pka1 mutant
por: Tanabe, Takuma, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c7e3a3e0b8ftgjv9d92qo5nimo