Specific Frontostriatal Circuits for Impaired Cognitive Flexibility and Goal-Directed Planning in Obsessive-Compulsive Disorder: Evidence From Resting-State Functional Connectivity

BACKGROUND: A recent hypothesis has suggested that core deficits in goal-directed behavior in obsessive-compulsive disorder (OCD) are caused by impaired frontostriatal function. We tested this hypothesis in OCD patients and control subjects by relating measures of goal-directed planning and cognitiv...

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Detalles Bibliográficos
Autores principales: Vaghi, Matilde M., Vértes, Petra E., Kitzbichler, Manfred G., Apergis-Schoute, Annemieke M., van der Flier, Febe E., Fineberg, Naomi A., Sule, Akeem, Zaman, Rashid, Voon, Valerie, Kundu, Prantik, Bullmore, Edward T., Robbins, Trevor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020061/
https://www.ncbi.nlm.nih.gov/pubmed/27769568
http://dx.doi.org/10.1016/j.biopsych.2016.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020061/
https://www.ncbi.nlm.nih.gov/pubmed/27769568
http://dx.doi.org/10.1016/j.biopsych.2016.08.009

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