Crystal structure, DFT calculations and evaluation of 2-(2-(3,4-dimethoxyphenyl)ethyl)isoindoline-1,3-dione as AChE inhibitor

Dioxoisoindolines have been included as a pharmacophore group in diverse drug-like molecules with a wide range of biological activity. Various reports have shown that phthalimide derivatives are potent inhibitors of AChE, a key enzyme involved in the deterioration of the cholinergic system during th...

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Detalles Bibliográficos
Autores principales: Andrade-Jorge, Erik, Bribiesca-Carlos, José, Martínez-Martínez, Francisco J., Soriano-Ursúa, Marvin A., Padilla-Martínez, Itzia I., Trujillo-Ferrara, José G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020091/
https://www.ncbi.nlm.nih.gov/pubmed/29938351
http://dx.doi.org/10.1186/s13065-018-0442-1

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