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H3K27 acetylation and gene expression analysis reveals differences in placental chromatin activity in fetal growth restriction
BACKGROUND: Posttranslational modification of histone tails such as histone 3 lysine 27 acetylation (H3K27ac) is tightly coupled to epigenetic regulation of gene expression. To explore whether this is involved in placenta pathology, we probed genome-wide H3K27ac occupancy by chromatin immunoprecipit...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020235/ https://www.ncbi.nlm.nih.gov/pubmed/29983832 http://dx.doi.org/10.1186/s13148-018-0508-x |