Identification of sonic hedgehog-regulated genes and biological processes in the cranial neural crest mesenchyme by comparative transcriptomics

BACKGROUND: The evolutionarily conserved Sonic Hedgehog (Shh) signaling pathway is essential for embryogenesis and orofacial development. SHH ligand secreted from the surface ectoderm activates pathway activity in the underlying cranial neural crest cell (cNCC)-derived mesenchyme of the developing u...

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Detalles Bibliográficos
Autores principales: Everson, Joshua L., Fink, Dustin M., Chung, Hannah M., Sun, Miranda R., Lipinski, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020285/
https://www.ncbi.nlm.nih.gov/pubmed/29945554
http://dx.doi.org/10.1186/s12864-018-4885-5

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