Membrane-bound and soluble forms of an NMDA receptor extracellular domain retain epitopes targeted in auto-immune encephalitis

BACKGROUND: Anti-NMDA receptor encephalitis (ANRE) is a potentially lethal disease attributed to auto-antibodies against the N-methyl-D-aspartate receptor (NMDAR). Full recovery is possible if therapy is initiated early in the disease course. Detection of ANRE antibodies in the cerebrospinal fluid (...

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Detalles Bibliográficos
Autores principales: Sharma, Rashmi, Al-Saleem, Fetweh H., Puligedda, Rama Devudu, Rattelle, Amy, Lynch, David R., Dessain, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020338/
https://www.ncbi.nlm.nih.gov/pubmed/29945600
http://dx.doi.org/10.1186/s12896-018-0450-1

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