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1,3- and 1,4-Benzdiyne equivalents for regioselective synthesis of polycyclic heterocycles
We have devised a novel 1,3-benzdiyne equivalent, capable of quadruple functionalization by sequential benzyne generation and reaction with arynophiles. The key features of this method include the chemoselective generation of two triple bonds in a single benzene ring under fluoride-mediated mild con...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020534/ https://www.ncbi.nlm.nih.gov/pubmed/30155171 http://dx.doi.org/10.1039/c6sc00798h |