Takeda G Protein-Coupled Receptor 5-Mechanistic Target of Rapamycin Complex 1 Signaling Contributes to the Increment of Glucagon-Like Peptide-1 Production after Roux-en-Y Gastric Bypass

BACKGROUND: The mechanism by which Roux-en-Y Gastric Bypass (RYGB) increases the secretion of glucagon-like peptide-1 (GLP-1) remains incompletely defined. Here we investigated whether TGR5-mTORC1 signaling mediates the RYGB-induced alteration in GLP-1 production in mice and human beings. METHODS: C...

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Detalles Bibliográficos
Autores principales: Zhai, Hening, Li, Zhi, Peng, Miao, Huang, Zhaoqi, Qin, Tingfeng, Chen, Linxi, Li, Hanbing, Zhang, Heng, Zhang, Weizhen, Xu, Geyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020750/
https://www.ncbi.nlm.nih.gov/pubmed/29859856
http://dx.doi.org/10.1016/j.ebiom.2018.05.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020750/
https://www.ncbi.nlm.nih.gov/pubmed/29859856
http://dx.doi.org/10.1016/j.ebiom.2018.05.026

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