Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes

Although psychotropic drugs act on neurons and glial cells, how glia respond, and whether glial responses are involved in therapeutic effects are poorly understood. Here, we show that fluoxetine (FLX), an anti-depressant, mediates its anti-depressive effect by increasing the gliotransmission of ATP....

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Detalles Bibliográficos
Autores principales: Kinoshita, Manao, Hirayama, Yuri, Fujishita, Kayoko, Shibata, Keisuke, Shinozaki, Youichi, Shigetomi, Eiji, Takeda, Akiko, Le, Ha Pham Ngoc, Hayashi, Hideaki, Hiasa, Miki, Moriyama, Yoshinori, Ikenaka, Kazuhiro, Tanaka, Kenji F., Koizumi, Schuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020856/
https://www.ncbi.nlm.nih.gov/pubmed/29887330
http://dx.doi.org/10.1016/j.ebiom.2018.05.036

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