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Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH
Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with macrophages is a key event determining the outcome of infection. Urease is a major virulence factor in C. neoformans but its role during macrophage interaction has not been characterized. Consequently, we analyz...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021110/ https://www.ncbi.nlm.nih.gov/pubmed/29906292 http://dx.doi.org/10.1371/journal.ppat.1007144 |