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Pluripotency Factors Functionally Premark Cell-Type-Restricted Enhancers in ESCs

While enhancers for embryonic stem cell (ESC)-expressed genes and lineage-determining factors are characterized by conventional marks of enhancer activation in ESCs(1,2,3), it remains unclear whether enhancers destined to regulate cell-type-restricted transcription units might also have some current...

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Detalles Bibliográficos
Autores principales: Kim, Hong Sook, Tan, Yuliang, Ma, Wubin, Merkurjev, Daria, Destici, Eugin, Ma, Qi, Suter, Tom, Ohgi, Kenneth, Skowronska-Krawczyk, Dorota, Friedman, Meyer, Rosenfeld, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021123/
https://www.ncbi.nlm.nih.gov/pubmed/29670286
http://dx.doi.org/10.1038/s41586-018-0048-8