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Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America

Introduction The objective is to report the dosimetry and safety profiles of the first fully automatized rotating gamma ray unit for intracranial radiosurgery in America. Methods Dosimetry tests were conducted by our institution using the standard of examination and calibration and the Intelligent γ...

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Autores principales: Lovo, Eduardo E, Campos, Fidel J, Caceros, Victor E, Minervini, Mario H, Reyes, William A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021186/
https://www.ncbi.nlm.nih.gov/pubmed/29963336
http://dx.doi.org/10.7759/cureus.2542
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author Lovo, Eduardo E
Campos, Fidel J
Caceros, Victor E
Minervini, Mario H
Reyes, William A
author_facet Lovo, Eduardo E
Campos, Fidel J
Caceros, Victor E
Minervini, Mario H
Reyes, William A
author_sort Lovo, Eduardo E
collection PubMed
description Introduction The objective is to report the dosimetry and safety profiles of the first fully automatized rotating gamma ray unit for intracranial radiosurgery in America. Methods Dosimetry tests were conducted by our institution using the standard of examination and calibration and the Intelligent γ Radiometer of the China Research Institute of Measurement. The phantom and dosimetry tests were performed by the Outreach Physics Section of MD Anderson Cancer Center and the Anchorage Radiation Therapy Center using the Radiation Therapy Oncology Group (RTOG) radiosurgery quality assurance guidelines. Clinically, 233 patients were treated. Results Mechanical precision was 0.16 mm and the offset registered at the phantom on all axes was 0.0. The ratio of the dose to the center was 0.97 (0.95-1.05), the ratio of the treated volume was 0.95 (0.75-1.25), the ratio of the measured treated volume to the volume of the target was 1.29 (1.00-2.00), the ratio of the minimal dose to the dose prescribed was 1.05 (>0.90), with a treated volume of 0.95 (0.75-1.25) and a minimum dose to target of 1.05 (>0.90). The dose rate at loading was 3.89 Gy per minute. None of the patients treated experienced severe complications. Conclusions The dosimetry studies are compliant with quality assurance standards for intracranial radiosurgery.
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spelling pubmed-60211862018-06-29 Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America Lovo, Eduardo E Campos, Fidel J Caceros, Victor E Minervini, Mario H Reyes, William A Cureus Medical Physics Introduction The objective is to report the dosimetry and safety profiles of the first fully automatized rotating gamma ray unit for intracranial radiosurgery in America. Methods Dosimetry tests were conducted by our institution using the standard of examination and calibration and the Intelligent γ Radiometer of the China Research Institute of Measurement. The phantom and dosimetry tests were performed by the Outreach Physics Section of MD Anderson Cancer Center and the Anchorage Radiation Therapy Center using the Radiation Therapy Oncology Group (RTOG) radiosurgery quality assurance guidelines. Clinically, 233 patients were treated. Results Mechanical precision was 0.16 mm and the offset registered at the phantom on all axes was 0.0. The ratio of the dose to the center was 0.97 (0.95-1.05), the ratio of the treated volume was 0.95 (0.75-1.25), the ratio of the measured treated volume to the volume of the target was 1.29 (1.00-2.00), the ratio of the minimal dose to the dose prescribed was 1.05 (>0.90), with a treated volume of 0.95 (0.75-1.25) and a minimum dose to target of 1.05 (>0.90). The dose rate at loading was 3.89 Gy per minute. None of the patients treated experienced severe complications. Conclusions The dosimetry studies are compliant with quality assurance standards for intracranial radiosurgery. Cureus 2018-04-27 /pmc/articles/PMC6021186/ /pubmed/29963336 http://dx.doi.org/10.7759/cureus.2542 Text en Copyright © 2018, Lovo et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Physics
Lovo, Eduardo E
Campos, Fidel J
Caceros, Victor E
Minervini, Mario H
Reyes, William A
Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America
title Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America
title_full Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America
title_fullStr Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America
title_full_unstemmed Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America
title_short Dosimetry and Treatment Descriptions Using the First Completely Automated Stereotactic Intracranial Radiosurgery Rotating Gamma Ray Unit in America
title_sort dosimetry and treatment descriptions using the first completely automated stereotactic intracranial radiosurgery rotating gamma ray unit in america
topic Medical Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021186/
https://www.ncbi.nlm.nih.gov/pubmed/29963336
http://dx.doi.org/10.7759/cureus.2542
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