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A versatile T cell-based assay to assess therapeutic antigen-specific PD-1-targeted approaches
Blockade of programmed cell death protein 1 (PD-1) immune checkpoint receptor signaling is an established standard treatment for many types of cancer and indications are expanding. Successful clinical trials using monoclonal antibodies targeting PD-1 signaling have boosted preclinical research, enco...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021243/ https://www.ncbi.nlm.nih.gov/pubmed/29963238 http://dx.doi.org/10.18632/oncotarget.25591 |